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L1040
Sigma
Livin β/ML-IAP human
>95% (SDS-PAGE), recombinant, expressed in Escherichia coli, buffered aqueous solution
| MDL number: | MFCD03702929 |
Description
| Analysis Note | Biological activity is measured by its ability to inhibit DEVD-afc cleavage in cell extracts activated by cytochrome c and dATP. |
| Physical form | Solution in 25 mM Hepes, pH 7.5, 0.1 M sodium chloride, and 1 mM dithiothreitol. |
| Biochem/physiol Actions | Livin β/ML-IAP, a member of the inhibitor of apoptosis (IAP) protein family, inhibits the activation of caspase 9 in cell extracts incubated with cytochrome c and dATP. |
Properties
| recombinant | expressed in Escherichia coli |
| assay | >95% (SDS-PAGE) |
| form | buffered aqueous solution |
| mol wt | mol wt 32 kDa by SDS-PAGE |
| Gene Information | human ... BIRC7(79444) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | NWG |
References
| reference | Kasof, G.M.,, Gomes, B.C. J. Biol. Chem. 276, 3238, (2001) |
| Ashhab, Y., et al. FEBS Lett. 495, 56, (2001) |
